research group leaders

Shaker Chuck Farah
Director of CEPID B3

Protein Structure and Function 

Graduated in Biochemistry and Chemistry from the University of Toronto (1985), Master’s in Biochemistry from the same institution (1988), and PhD in Biological Sciences (Biochemistry) from the Universidade de São Paulo (USP, 1994). Currently, he is a Full Professor in the Department of Biochemistry at the Instituto de Química and Vice-Dean of the IQ-USP. The focus of his research is to understand the structural basis of processes important for complex bacterial behaviors, using as a model the phytopathogen Xanthomonas citri, the causative agent of citrus canker. 

E-mail: chsfarah@iq.usp.br

 (11) 97400-3454

Aline Maria da Silva
Research group leader and Vice-Director (2023-2024

Molecular characterization of bacteriophages and determinants of phage-bacterium interaction. 

Graduated in Pharmaceutical Sciences and PhD in Biochemistry from the Universidade de São Paulo (USP), with postdoctoral studies at the Saint Louis University School of Medicine, Saint Louis, USA. Since 1991, she has been a faculty member in the Department of Biochemistry at the IQ-USP, working on the isolation and characterization of bacteriophages and determinants of phage-bacterium interaction, aiming for applications in phage therapy. 

E-mail: almsilva@iq.usp.br ou almdsilva@gmail.com

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Beny Spira
Research group leader, Education and Outreach Coordinator

Adaptation, mutagenesis, and evolution of bacteria

PhD from Tel-Aviv University and postdoctoral studies at the University of Sydney. Currently, he is an Associate Professor III at the ICB-USP and Coordinator of the Laboratory of Bacterial Genetics. The focus of his research is the study of mutagenesis systems and adaptation/evolution of bacteria to the environment and mechanisms of antibiotic resistance and tolerance. 

E-mail: benys@usp.br

 11 30918346

Cristiane Rodrigues Guzzo Carvalho
Research group leader

Structural and functional study of secretory systems and bacterial c-di-GMP signaling. Structural study of respiratory virus proteins.

Graduated in Chemistry with technological attributes and in Biotechnology (2005), PhD and postdoctoral studies (2011) in Biological Sciences (Biochemistry) from the Universidade de São Paulo. In 2015-2016, she participated in a sabbatical project in the laboratory of Professor Gabriel Waksman (London), exploring additional structural biology techniques. Currently, she studies bacterial secretory systems, signaling, and biochemistry of the SARS-CoV-2 virus at the Instituto de Ciências Biomédicas da Universidade de São Paulo, incorporating molecular biology, protein expression, structural biology techniques, and conventional biochemistry methods. 

E-mail: crisguzzo@usp.br ou crisguzzo@gmail.com

Cristina Unicamp perfil
Cristina Elisa Alvarez Martinez
Research group leader

Gene Regulation in Bacteria; Bacterial Secretion Systems 

Graduated in Biological Sciences from the Universidade Federal do Rio de Janeiro (UFRJ), Master’s in Molecular Biology from the Instituto de Biofísica Carlos Chagas Filho (UFRJ), and PhD in Biochemistry at the IQ-USP. Postdoctoral studies at the University of Texas Health Science Center at Houston. She leads studies on protein secretion systems by pathogenic bacteria for plants (Xanthomonas sp.) and animals (Stenotrophomonas sp. and Acinetobacter sp.) at the Instituto de Biologia da Universidade Estadual de Campinas (UNICAMP), as well as research on transcriptional regulators, seeking to unravel the role of important regulator families in bacterial responses to environmental variations.

E-mail: ceamarti@unicamp.br

Frederico Gueiros Filho é Professor Associado do Depto de Bioquímica - IQ USP - Foto: Cecília Bastos/USP Imagem
Frederico J. Gueiros Filho
 Research group leader, Innovation Coordinator 

Molecular mechanisms controlling bacterial growth and division 

He earned his PhD from Harvard University in 1998, followed by postdoctoral training with Rich Losick (Harvard MCB) from 1998 to 2002. Since 2003, his laboratory at the IQ-USP has studied the molecular mechanisms that allow bacterial cells to grow and divide, in addition to contributing to validating new antibiotic targets.

E-mail: fgueiros@iq.usp.br

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Germán Gustavo Sgro

Research group leader

Structural, molecular, and functional characterization of macro-protein complexes of interest in microbiology 

University Bachelor with a mention in Chemistry (2005), Licentiate in Biotechnology (2009), and postgraduate as a Doctor in Biological Sciences (2014) from the Facultad de Ciencias Bioquímicas y Farmacéuticas of the Universidad Nacional de Rosario, Argentina. He worked as a postdoctoral researcher at the Instituto de Química da Universidade de São Paulo (USP, 2014-2019) under the supervision of Professor Shaker Chuck Farah. He served as a Professor in the course ‘A Proposal to Read, Write, and Learn Better Upon Entering University’ (2008-2010) and as an Assistant in the Department of Organic Chemistry (2010-2012) at the Facultad de Ciencias Bioquímicas y Farmacéuticas of the Universidad Nacional de Rosario, Argentina. He also worked as an Assistant in the chair of Cell Biology and the Bromatology Laboratory (2012-2013) in the Technical University Course in Chemistry at the Instituto Politécnico Superior ‘General San Martin’, at the Universidad Nacional de Rosario, Argentina. He completed an internship (2016-2017) in the Department of Biological Sciences at Birkbeck College in London, UK, where he held the position of Associate Research Fellow. 

Currently, he is a Professor Doctor in the Department of BioMolecular Sciences at the Faculdade de Ciências Farmacêuticas de Ribeirão Preto da Universidade de São Paulo.

E-mail: ggsgro@usp.br

Henrique Ferreira
Research group leader

Biology of bacteria and their viruses. 

Graduated in Biological Sciences (1995) and Master’s in Molecular and Microbial Genetics from the Universidade Estadual de Campinas (UNICAMP, 1998). PhD in Biochemistry from the University of Oxford, UK (2002), where he worked on chromosomal integrity and site-specific recombination in the group of Professor David Sherratt. Postdoctoral studies on the theme of bacterial chromosome segregation in the group of Professor Jeff Errington (2002-2004), Sir William Dunn School of Pathology, University of Oxford, UK. Postdoctoral studies investigating protein function based on structure at LNLS-Campinas (2004-2006). FAPESP Young Researcher (2006-2009). Currently, he is an Adjunct Professor 3 in the Department of Biochemistry and Microbiology, Instituto de Biociências de Rio Claro, SP (UNESP). He coordinates a research group investigating various aspects of bacterial biology, with a greater emphasis on chromosomal dynamics and cell division of the phytopathogen Xanthomonas citri, the causative agent of citrus canker. He also works on the development of agricultural pesticides using natural, synthetic, and bacteriophage active compounds. 

E-mail: henrique.ferreira@unesp.br

João Carlos Setubal
Research group leader and Vice-Director (2024-current) 

Genomics, metagenomics, and bioinformatics. 

PhD in computing from the University of Washington. He works on the development and use of computational tools for omics data analysis, with an emphasis on genomics and metagenomics. 

E-mail: setubal@iq.usp.br

José Freire da Silva Neto
Research group leader

Molecular Genetics of Bacteria

Graduated in Biological Sciences from the Instituto de Biociências da Universidade de São Paulo (IB-USP) and PhD in Microbiology from the Instituto de Ciências Biomédicas (ICB-USP). He completed postdoctoral studies at ICB-USP and IB-USP and earned his Habilitation from the Faculdade de Medicina de Ribeirão Preto (FMRP-USP). Currently, he is an Associate Professor at FMRP-USP, Coordinator of the Graduate Program in Cell and Molecular Biology at FMRP-USP, and CNPq PQ2 fellow. He develops projects in the following research areas: Gene Expression Regulation, Bacterial Pathogenicity, Metal Homeostasis Mechanisms and Nutritional Immunity, Bacterial Secretion Systems. The main organism used is the environmental pathogen bacterium Chromobacterium violaceum.  

 

E-mail: jfsneto@usp.br

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Leonardo Talachia Rosa
Research group leader

Bacterial metabolism/ Structural Biology 

Professor at the Instituto de Biologia da Universidade Estadual de Campinas (IB-UNICAMP) and Young Researcher funded by the Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Currently, he works with membrane transporters in the bacterium Bordetella pertussis. He holds a PhD from The University of Sheffield, postdoctoral studies at the European Institute of Chemistry and Biology, and postdoctoral studies at the IQ-USP. Fascinated by bacterial metabolism, he is particularly interested in the characterization of biological processes by structural biology and CryoEM. 

E-mail: leotrosa@unicamp.br

Marcelo Brocchi
Research group leader 

Bacterial pathogenicity 

He holds a Master’s (1990-1993) and PhD (1993-1997) in Microbial Genetics from the Universidade Estadual de Campinas (UNICAMP). Part of the PhD project was carried out at IRIS Siena, Italy (1993-1995). He completed his postdoctoral studies (1997-1998) at UNICAMP, developing research on bacterial pathogenicity. He began his career in 1998 as a professor-doctor in Microbiology at the Universidade de São Paulo (USP), Faculdade de Medicina de Ribeirão Preto. In 2004, he moved to UNICAMP, as a professor-doctor (2004-2007) and as an associate since 2007. The research in the laboratory is related to the study of the pathogenicity of Gram-negative bacteria. The group also works on the development of bacterial mutants to study gene function and virulence attenuation. One of the strategies involves the attenuation of S. enterica strains by deletion of genes encoding nucleoid-associated proteins (NAPs). Recently, the group began investigating the mechanisms of resistance and mode of action of antimicrobials. 

E-mail: mbrocchi@unicamp.br ou marbrocchi@gmail.com

Marcio Vinicius Bertacine Dias
Research group leader 

Structural Biology, Mycobacteria, Actinomycetes, Antimicrobials

Graduated in Biological Sciences from the Instituto de Biociências, Letras e Ciências Exatas da Universidade Estadual Paulista (UNESP-IBILCE) with a PhD in Molecular Biophysics from the same institution. He completed postdoctoral studies at the University of Cambridge, developing projects in the area of biosynthesis of natural products and the application of the fragment-based drug development approach. Currently, he is an Associate Professor in the Department of Microbiology at the ICB-USP. He works with structural biology and other biophysical techniques in the study of microbial enzymes.  

E-mail: mvbdias@usp.br

Marco Aurélio Takita
 Research group leader 

 Research group leader 

Biologist graduated from the Universidade de São Paulo (USP) with a PhD in Sciences (Biochemistry) from the Instituto de Química (IQ), also at USP, and postdoctoral studies at the Salk Institute for Biological Studies (CA, USA). Currently, he is a Researcher VI at the Centro de Citricultura Sylvio Moreira – Instituto Agronômico (IAC) and a CNPq Productivity Fellow 1D. In addition to a CEPID membership, he is a PP in a FAPESP thematic project on the microbiome and in an INCT (FAPESP/CNPq) and also participates in a FAPESP NPOP on gene editing in citrus. 

E-mail: marco.takita@ccsm.br

Marilis do Valle Marques
Research group leader

Gene regulation in bacterial stress response 

Graduated in Biological Sciences from the Universidade Estadual de Campinas (UNICAMP), PhD in Biochemistry from the Universidade de São Paulo (USP), and postdoctoral studies in Molecular Biology at the University of California (UCLA). Currently, she is an Associate Professor 3 in the Department of Microbiology at USP. She has projects in the area of gene regulation in the bacterium Caulobacter, together with collaborators from Brazil and abroad. 

E-mail: mvmarque@usp.br

Regina Lúcia Baldini

Research group leader  

Research group leader  

Graduated in Biological Sciences from the Universidade Estadual de Campinas (UNICAMP), with a Master’s in Genetics from the same institution and a PhD in Biochemistry from the Instituto de Química da Universidade de São Paulo (IQ-USP). Postdoctoral studies at Massachusetts General Hospital/Harvard Medical School, she was a Young Researcher in the Department of Microbiology (ICB-USP). She was hired as a faculty member in 2005 at the IQ-USP, where she is now an Associate Professor. She researches gene expression and signaling in bacteria.

E-mail: baldini@iq.usp.br ou rlbaldini@usp.br

Rita de Cassia Café Ferreira
Research group leader

Research and Teaching in Microbiology 

Graduated in Biological Sciences from the Universidade Federal do Rio de Janeiro (UFRJ) and PhD from the Instituto de Biofísica Carlos Chagas Filho (1996). She has been a professor-doctor in the Department of Microbiology at the Universidade de São Paulo (USP) since 2000. She works in Microbiology Education as coordinator of the Adote Project (2013). Responsible for the Education area at the Brazilian Society of Microbiology since 2018. 

E-mail: ritacafe@usp.br

Roberto Kopke Salinas
Research group leader

RMN protein

Graduated in Chemistry (1996) and Master’s in Biochemistry (2000) from the Universidade de São Paulo (USP, 2000). He holds a PhD in Chemistry from Utrecht University, Netherlands (2005), and postdoctoral studies at USP (2005-2008) and Florida State University (2009-2011). Currently, he is an Associate Professor in the Department of Biochemistry at the IQ-USP. Experienced in Biophysics, with an emphasis on Molecular Biophysics, working mainly on the application of Nuclear Magnetic Resonance methods to study protein structure and dynamics in solution. 

E-mail: roberto@iq.usp.br ou rsalinas@usp.br

Robson Francisco de Souza
Bioinformatics Module Coordinator 

Comparative genomics / Protein Evolution and Classification

Bachelor in Molecular Sciences, Master’s in Sciences (Biotechnology), and PhD in Sciences (Biochemistry) from the Universidade de São Paulo (USP). Postdoctoral studies in Bioinformatics at the National Center for Biotechnology Information (NCBI), National Library of Medicine, NIH/USA. He develops research in the area of protein evolution and classification, as well as comparative genome analysis with a focus on identifying putative functions of gene families and analyzing the evolutionary history of viruses, microorganisms, and biomolecular systems. 

E-mail: rfsouza@usp.br

Rodrigo Galhardo
Rodrigo da Silva Galhardo
Research group leader 

Genetics and Molecular Biology of bacteria, with emphasis on: mobile elements, DNA repair and mutagenesis, control of gene expression. 

 

Biologist from the Universidade Federal do Rio de Janeiro (UFRJ), with a Master’s in Biophysics from UFRJ. PhD in Microbiology from the Universidade de São Paulo (USP), Postdoctoral studies at USP and Baylor College of Medicine with a scholarship from the PEW Latin American Fellows program. Professor in the Department of Microbiology at the ICB-USP since 2011, and Associate Professor since 2022. He has research projects on the biology of integrative and conjugative elements of Proteus mirabilis and on the SOS response of Pseudomonas aeruginosa and Caulobacter crescentus. CNPq Level 2 Researcher. 

E-mail: rgalhard@usp.br

Sandro Roberto Marana
Research group leader

Catalysis and Thermostability in Enzymes

Graduated in Biological Sciences from the Instituto de Biociências da Universidade de São Paulo (USP, 1991). Master’s (1994), PhD (1999), and Postdoctoral studies (2001) in Biological Sciences – Biochemistry from the IQ-USP. Associate Professor at the IQ-USP since 2001. He works in the area of Biochemistry with a focus on Enzymology.

E-mail: srmarana@iq.usp.br